BACE2 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715130

This Recombinant BACE2 protein is expressed in HEK-293 Cells.

Quick Overview for BACE2 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2715130)

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant A

Purification tag / Conjugate: This BACE2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human BACE2 (transcript variant a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Alternative Name: Bace2

Background: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer&aposs disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Molecular Weight: 49.8 kDa

NCBI Accession: NP_036237