Desmocollin 2 Protein (DSC2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719414

This Recombinant Desmocollin 2 protein is expressed in HEK-293 Cells.

Quick Overview for Desmocollin 2 Protein (DSC2) (Myc-DYKDDDDK Tag) (ABIN2719414)

Target: Desmocollin 2 (DSC2)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Desmocollin 2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Desmocollin-2 (transcript variant Dsc2a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Desmocollin 2 (DSC2)

Alternative Name: Desmocollin-2

Background: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.

Molecular Weight: 97 kDa

NCBI Accession: NP_077740