DISC1 Protein (Transcript Variant L) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719502

Recombinant DISC1 protein expressed in HEK-293 Cells.

Quick Overview for DISC1 Protein (Transcript Variant L) (Myc-DYKDDDDK Tag) (ABIN2719502)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant L

Purification tag / Conjugate: This DISC1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human DISC1 (transcript variant L) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: Disc1

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(111)(q42.1q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 93.4 kDa

NCBI Accession: NP_061132

Pathways: Regulation of Cell Size