Quick Overview for DNAJA1 Protein (Myc-DYKDDDDK Tag) (ABIN2719565)
Target
See all DNAJA1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This DNAJA1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human DNAJA1 / HDJ2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1) (AA 1-394) protein (His-IF2DI Tag)
DNAJA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1) (AA 1-397) protein (GST tag)DNAJA1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- DNAJA1 (DnaJ (Hsp40) Homolog, Subfamily A, Member 1 (DNAJA1))
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Alternative Name
- Dnaja1,hdj2
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Background
- This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes.
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Molecular Weight
- 44.7 kDa
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NCBI Accession
- NP_001530
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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