DNMT3L Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for DNMT3L Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2719619)
Target
See all DNMT3L (TRDMT1) ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Protein Characteristics
- Transcript Variant 2
-
Purification tag / Conjugate
- This DNMT3L protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human DNMT3L (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $12,595.45Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $19,692.86Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
-
Alternative Name
- Dnmt3l
-
Background
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
Molecular Weight
- 43.4 kDa
-
NCBI Accession
- NP_787063
Target
-