Dynamin 1-Like Protein (DNM1L) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719859

Recombinant Dynamin 1-Like protein expressed in HEK-293 Cells.

Quick Overview for Dynamin 1-Like Protein (DNM1L) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2719859)

Target: Dynamin 1-Like (DNM1L)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This Dynamin 1-Like protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Dynamin-1-like protein (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Dynamin 1-Like (DNM1L)

Alternative Name: Dynamin-1-Like Protein

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 79.3 kDa

NCBI Accession: NP_036193