Endothelin 1 Protein (EDN1) (Myc-DYKDDDDK Tag)
Quick Overview for Endothelin 1 Protein (EDN1) (Myc-DYKDDDDK Tag) (ABIN2720181)
Target
See all Endothelin 1 (EDN1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Endothelin 1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Endothelin-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Endothelin 1 (EDN1) (AA 113-212) protein (GST tag)
EDN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelin 1 (EDN1) (AA 54-202) (Active) protein (His tag)EDN1 Origin: Rat Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
Endothelin 1 (EDN1) (AA 1-212) protein (GST tag)EDN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelin 1 (EDN1) (AA 53-90) protein (His-IF2DI Tag)EDN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Endothelin 1 (EDN1) (AA 53-73) (Active) protein (GST tag)EDN1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Endothelin 1 (EDN1)
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Alternative Name
- Endothelin-1
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Background
- This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 22.4 kDa
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NCBI Accession
- NP_001946
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Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
Target
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