EPH Receptor A8 Protein (EPHA8) (DYKDDDDK-His Tag)

Catalog No. ABIN2720244

This Recombinant EPH Receptor A8 protein is produced in HEK-293 Cells.

Quick Overview for EPH Receptor A8 Protein (EPHA8) (DYKDDDDK-His Tag) (ABIN2720244)

Target: EPH Receptor A8 (EPHA8)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This EPH Receptor A8 protein is labelled with DYKDDDDK-His Tag.

Characteristics:

• Recombinant human EPHA8 (C-term DDK/His tag, transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: EPH Receptor A8 (EPHA8)

Alternative Name: Epha8

Background: This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.

Molecular Weight: 60 kDa

NCBI Accession: NP_065387

Pathways: RTK Signaling