EPSTI1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for EPSTI1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2720357)
Target
See all EPSTI1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This EPSTI1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human EPSTI1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Epithelial Stromal Interaction 1 (Breast) (EPSTI1) (AA 1-410) protein (GST tag)
EPSTI1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Epithelial Stromal Interaction 1 (Breast) (EPSTI1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)EPSTI1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- EPSTI1 (Epithelial Stromal Interaction 1 (Breast) (EPSTI1))
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Alternative Name
- Epsti1
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Background
- The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE).
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Molecular Weight
- 47.3 kDa
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NCBI Accession
- NP_001002264
Target
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