FERMT3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721017

Recombinant FERMT3 protein expressed in HEK-293 Cells.

Quick Overview for FERMT3 Protein (Myc-DYKDDDDK Tag) (ABIN2721017)

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This FERMT3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human FERMT3 (transcript variant URP2SF) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: Fermt3

Background: Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 75.2 kDa

NCBI Accession: NP_113659