FMR1 Protein (Myc-DYKDDDDK Tag)
This Recombinant FMR1 protein is expressed in HEK-293 Cells.
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Catalog No. ABIN2721259
$1,112.40
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20 μg
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United States
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Quick Overview for FMR1 Protein (Myc-DYKDDDDK Tag) (ABIN2721259)
Target
See all FMR1 Proteins
FMR1
(Fragile X Mental Retardation 1 (FMR1))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This FMR1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human FMR1 / FMRP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Fragile X Mental Retardation 1 (FMR1) (AA 1-297) protein (GST tag)
FMR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fragile X Mental Retardation 1 (FMR1) (AA 121-220) protein (GST tag)FMR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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Alternative Name
- Fmr1,fmrp
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Background
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
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Molecular Weight
- 71 kDa
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NCBI Accession
- NP_002015
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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