FOXO3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for FOXO3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2721367)
Target
See all FOXO3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This FOXO3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human FOXO3 / FKHRL1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Forkhead Box O3 (FOXO3) (AA 1-672) protein (His tag)
custom-made FOXO3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box O3 (FOXO3) (AA 1-673) protein (His tag)custom-made FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Forkhead Box O3 (FOXO3) (AA 1-673) protein (GST tag)FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (AA 478-673) protein (His-IF2DI Tag)FOXO3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Forkhead Box O3 (FOXO3) (AA 361-460) protein (GST tag)FOXO3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Forkhead Box O3 (FOXO3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)FOXO3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." in: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).
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: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." in: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- Foxo3,fkhrl1
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Background
- This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
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Molecular Weight
- 71.1 kDa
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NCBI Accession
- NP_963853
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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