Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721522

This Recombinant Glucose-6-Phosphate Dehydrogenase protein is produced in HEK-293 Cells.

Quick Overview for Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2721522)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This Glucose-6-Phosphate Dehydrogenase protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human G6PD (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: g6pd

Background: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 59.1 kDa

NCBI Accession: NP_001035810

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones