Gelsolin Protein (GSN) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721787

This Recombinant Gelsolin protein is expressed in HEK-293 Cells.

Quick Overview for Gelsolin Protein (GSN) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2721787)

Target: Gelsolin (GSN)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Gelsolin protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Gelsolin (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Gelsolin (GSN)

Alternative Name: Gelsolin

Background: The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Molecular Weight: 82.9 kDa

NCBI Accession: NP_000168

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy