UBE2K Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for UBE2K Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722758)
Target
See all UBE2K ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This UBE2K protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human HIP2 / UBE2K (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (GST tag)
UBE2K Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (His-IF2DI Tag)UBE2K Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (His tag)UBE2K Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
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Alternative Name
- Hip2,ube2k
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Background
- The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
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Molecular Weight
- 22.2 kDa
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NCBI Accession
- NP_005330
Target
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