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HRG Protein (Myc-DYKDDDDK Tag)

HRG Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722778
  • Target See all HRG Proteins
    HRG (Histidine-Rich Glycoprotein (HRG))
    Protein Type
    Recombinant
    Origin
    • 7
    • 4
    • 3
    • 1
    Human
    Source
    • 5
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This HRG protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Histidine-rich glycoprotein / HRG protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product HRG Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    HRG (Histidine-Rich Glycoprotein (HRG))
    Alternative Name
    Histidine-Rich Glycoprotein,hrg (HRG Products)
    Synonyms
    AI265597 Protein, AW413091 Protein, D16jh2 Protein, D18020 Protein, Hprg Protein, Hrgp Protein, HPRG Protein, HRGP Protein, THPH11 Protein, HRG1 Protein, histidine rich glycoprotein Protein, histidine-rich glycoprotein Protein, HRG Protein, LOAG_12427 Protein, LOC100597044 Protein, Hrg Protein
    Background
    This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein&aposs effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
    Molecular Weight
    57.6 kDa
    NCBI Accession
    NP_000403
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