HMGB2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for HMGB2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722873)
Target
See all HMGB2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This HMGB2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human HMGB2 / HMG2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- HMGB2 (High Mobility Group Box 2 (HMGB2))
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Alternative Name
- Hmgb2,hmg2
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Background
- This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
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Molecular Weight
- 23.9 kDa
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NCBI Accession
- NP_002120
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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