BIRC3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for BIRC3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2723206)
Target
See all BIRC3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This BIRC3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IAP1 / BIRC3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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Alternative Name
- Iap1,birc3
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Background
- This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
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Molecular Weight
- 68.2 kDa
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NCBI Accession
- NP_001156
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Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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