BIRC2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for BIRC2 Protein (Myc-DYKDDDDK Tag) (ABIN2723209)
Target
See all BIRC2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This BIRC2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IAP2 / BIRC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
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Alternative Name
- Iap2,birc2
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Background
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 69.7 kDa
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NCBI Accession
- NP_001157
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Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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