IL17RD Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723368

This Recombinant IL17RD protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for IL17RD Protein (Myc-DYKDDDDK Tag) (ABIN2723368)

Target: IL17RD (Interleukin 17 Receptor D (IL17RD))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This IL17RD protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human IL17RD protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Mellett, Atzei, Bergin, Horgan, Floss, Wurst, Callanan, Moynagh: "Orphan receptor IL-17RD regulates Toll-like receptor signalling via SEFIR/TIR interactions." in: Nature communications, Vol. 6, pp. 6669, (2015) (PubMed).

Target Details

Target: IL17RD (Interleukin 17 Receptor D (IL17RD))

Alternative Name: Il17rd

Background: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

Molecular Weight: 82.2 kDa

NCBI Accession: NP_060033

Pathways: Toll-Like Receptors Cascades