ILF2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for ILF2 Protein (Myc-DYKDDDDK Tag) (ABIN2723410)
Target
See all ILF2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ILF2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ILF2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))
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Alternative Name
- Ilf2
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Background
- The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.
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Molecular Weight
- 42.9 kDa
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NCBI Accession
- NP_004506
Target
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