INHBA Protein
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- Target See all INHBA Proteins
- INHBA (Inhibin, beta A (INHBA))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Inhibin beta A chain (INHBA) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 was determined by its ability to inhibit the proliferation of murine MPC-11 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.
- Top Product
- Discover our top product INHBA Protein
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Inhibin, beta A (INHBA) protein (His tag)
INHBA Origin: Human Host: Tobacco (Nicotiana benthamiana) Recombinant > 97 % by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue. WB
Inhibin, beta A (INHBA) (AA 311-426) protein (His-IF2DI Tag)INHBA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Inhibin, beta A (INHBA) (AA 1-426) protein (GST tag)INHBA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- INHBA (Inhibin, beta A (INHBA))
- Alternative Name
- Inhibin beta A Chain (Inhba) (INHBA Products)
- Synonyms
- EDF Protein, FRP Protein, actba Protein, inhba Protein, inhbaa-001 Protein, edf Protein, frp Protein, INHB Protein, inhbal Protein, zgc:158348 Protein, inhibin beta A subunit Protein, inhibin beta-A Protein, inhibin, beta Aa Protein, inhibin beta A Protein, inhibin, beta Ab Protein, INHBA Protein, Inhba Protein, inhbaa Protein, inhba Protein, inhbab Protein
- Background
- This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
- Molecular Weight
- 26 kDa
- NCBI Accession
- NP_002183
- Pathways
- Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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