PDX1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PDX1 Protein (Myc-DYKDDDDK Tag) (ABIN2723514)
Target
See all PDX1 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This PDX1 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human Insulin promoter factor 1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $13,686.36Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
-
Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-284) protein (His tag)
custom-made PDX1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-283) protein (His tag)custom-made PDX1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-283) protein (GST tag)PDX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pancreatic and Duodenal Homeobox 1 (PDX1) protein (His tag)PDX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
-
Alternative Name
- Insulin Promoter Factor 1
-
Background
- Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. [UniProtKB/Swiss-Prot Function]
-
Molecular Weight
- 30.6 kDa
-
NCBI Accession
- NP_000200
-
Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
Target
-
