IL16 Protein (Transcript Variant 3)
Quick Overview for IL16 Protein (Transcript Variant 3) (ABIN2723625)
Target
See all IL16 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
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Characteristics
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- Recombinant human Interleukin-16 / IL16 (transcript variant 3) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
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Biological Activity Comment
- Specific Activity is greater than 1.0 x 104 IU/mg as determined by the ability of Recombinant IL-16 to chemoattract human CD4+ T lymphocytes using a concentration range of 10.0-100.0 ng/ml
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Interleukin 16 (IL16) (AA 1-1322) protein (His tag)
custom-made IL16 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1-1332) protein (His tag)custom-made IL16 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Interleukin 16 (IL16) (AA 1203-1332) (Active) protein (His tag)IL16 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 16 (IL16) (AA 1-454) protein (GST tag)IL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 16 (IL16) (AA 502-631) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
Interleukin 16 (IL16) proteinIL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant 95,00% SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL16 (Interleukin 16 (IL16))
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Alternative Name
- Interleukin-16,il16
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Background
- Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells. [UniProtKB/Swiss-Prot Function]
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Molecular Weight
- 13.3 kDa
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NCBI Accession
- NP_001165599
Target
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