IL23A Protein (Myc-DYKDDDDK Tag)
Quick Overview for IL23A Protein (Myc-DYKDDDDK Tag) (ABIN2723682)
Target
See all IL23A ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IL23A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Interleukin-23 alpha / IL23A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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Alternative Name
- Interleukin-23 Alpha,il23a
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Background
- This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
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Molecular Weight
- 18.6 kDa
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NCBI Accession
- NP_057668
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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