IRF3 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
Quick Overview for IRF3 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag) (ABIN2723794)
Target
See all IRF3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 4
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Purification tag / Conjugate
- This IRF3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IRF3 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IRF3 (Interferon Regulatory Factor 3 (IRF3))
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Alternative Name
- Irf3
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Background
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Molecular Weight
- 33.6
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NCBI Accession
- NP_001184053
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Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Target
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