IRF8 Protein (Myc-DYKDDDDK Tag)
Quick Overview for IRF8 Protein (Myc-DYKDDDDK Tag) (ABIN2723812)
Target
See all IRF8 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IRF8 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IRF8 / ICSBP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IRF8 (Interferon Regulatory Factor 8 (IRF8))
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Alternative Name
- Irf8,icsbp1
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Background
- Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
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Molecular Weight
- 48.2 kDa
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NCBI Accession
- NP_002154
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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