IRF8 Protein (AA 1-424, full length) (His-SUMO Tag)
-
- Target See all IRF8 Proteins
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-424
-
Origin
- Mouse
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IRF8 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MCDRNGGRRL RQWLIEQIDS SMYPGLIWEN DEKTMFRIPW KHAGKQDYNQ EVDASIFKAW AVFKGKFKEG DKAEPATWKT RLRCALNKSP DFEEVTDRSQ LDISEPYKVY RIVPEEEQKC KLGVAPAGCM SEVPEMECGR SEIEELIKEP SVDEYMGMTK RSPSPPEACR SQILPDWWVQ QPSAGLPLVT GYAAYDTHHS AFSQMVISFY YGGKLVGQAT TTCLEGCRLS LSQPGLPKLY GPDGLEPVCF PTADTIPSER QRQVTRKLFG HLERGVLLHS NRKGVFVKRL CQGRVFCSGN AVVCKGRPNK LERDEVVQVF DTNQFIRELQ QFYATQSRLP DSRVVLCFGE EFPDTVPLRS KLILVQVEQL YARQLVEEAG KSCGAGSLMP ALEEPQPDQA FRMFPDICTS HQRPFFRENQ QITV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product IRF8 Protein
-
Interferon Regulatory Factor 8 (IRF8) (AA 1-426) protein (GST tag)
IRF8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 8 (IRF8) (AA 122-218) protein (GST tag)IRF8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 8 (IRF8) protein (Myc-DYKDDDDK Tag)IRF8 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- IRF8 (Interferon Regulatory Factor 8 (IRF8))
- Alternative Name
- IRF8 (IRF8 Products)
- Synonyms
- zgc:92252 Protein, IRF8 Protein, MGC140338 Protein, DKFZp469B0320 Protein, H-ICSBP Protein, ICSBP Protein, ICSBP1 Protein, IRF-8 Protein, icsbp1 Protein, AI893568 Protein, Icsbp1 Protein, Myls Protein, interferon regulatory factor 8 Protein, interferon regulatory factor 8 L homeolog Protein, irf8 Protein, IRF8 Protein, irf8.L Protein, Irf8 Protein
- Background
- Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune syst. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory elent, followed by cooperative binding of BATF and IRF8 and activation of genes.
- Molecular Weight
- 64.21 kDa
- UniProt
- P23611
- Pathways
- Cellular Response to Molecule of Bacterial Origin
-
