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ITPA Protein (Transcript Variant 1) (His tag)

Recombinant ITPA protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2723912
$480.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
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Quick Overview for ITPA Protein (Transcript Variant 1) (His tag) (ABIN2723912)

Target

See all ITPA Proteins
ITPA (Inosine Triphosphatase (ITPA))

Protein Type

Recombinant

Origin

  • 13
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Human

Source

  • 11
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  • 1
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Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This ITPA protein is labelled with His tag.

    Characteristics

    • Recombinant human ITPA (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone

    Endotoxin Level

    < 0.1 EU per μg protein as determined by LAL test
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    20 mM Tris-HCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    ITPA (Inosine Triphosphatase (ITPA))

    Alternative Name

    Itpa

    Background

    This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

    Molecular Weight

    22.5 kDa

    NCBI Accession

    NP_258412
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