UVSSA/KIAA1530 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724212

Recombinant UVSSA/KIAA1530 protein expressed in HEK-293 Cells.

Quick Overview for UVSSA/KIAA1530 Protein (Myc-DYKDDDDK Tag) (ABIN2724212)

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This UVSSA/KIAA1530 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human KIAA1530 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))

Alternative Name: Kiaa1530

Background: The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.

Molecular Weight: 80.4 kDa

NCBI Accession: NP_065945