Kallikrein 6 Protein (KLK6) (Transcript Variant B) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724326

Recombinant Kallikrein 6 protein expressed in HEK-293 Cells.

Quick Overview for Kallikrein 6 Protein (KLK6) (Transcript Variant B) (Myc-DYKDDDDK Tag) (ABIN2724326)

Target: Kallikrein 6 (KLK6)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant B

Purification tag / Conjugate: This Kallikrein 6 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human KLK6 / Kallikrein-6 (transcript variant B) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Kallikrein 6 (KLK6)

Alternative Name: Klk6,kallikrein-6

Background: This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer&aposs and Parkinson&aposs disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molecular Weight: 25.1 kDa

NCBI Accession: NP_001012982

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling