Kallikrein 7 Protein (KLK7) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724331

This Recombinant Kallikrein 7 protein is expressed in HEK-293 Cells.

Quick Overview for Kallikrein 7 Protein (KLK7) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2724331)

Target: Kallikrein 7 (KLK7)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Kallikrein 7 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human KLK7 / Kallikrein-7 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Kallikrein 7 (KLK7)

Alternative Name: Klk7,kallikrein-7

Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Molecular Weight: 27.3 kDa

NCBI Accession: NP_005037

Pathways: Complement System