KREMEN1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
Quick Overview for KREMEN1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag) (ABIN2724425)
Target
See all KREMEN1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 4
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Purification tag / Conjugate
- This KREMEN1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Kringle containing transmembrane protein 1 (KREMEN1), transcript variant 4 (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 21-392) (Active) protein (hFc Tag)
KREMEN1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Kringle Containing Transmembrane Protein 1 (KREMEN1) (AA 21-392) (Active) protein (Fc Tag)KREMEN1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
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Background
- This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
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Molecular Weight
- 48.3 kDa
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NCBI Accession
- NP_001034660
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Pathways
- WNT Signaling
Target
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