KREMEN1 Protein (AA 21-392) (Fc Tag)
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- Target See all KREMEN1 Proteins
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 21-392
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KREMEN1 protein is labelled with Fc Tag.
- Characteristics
- Human Kremen-1 protein, Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KREMEN1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
- Alternative Name
- KREMEN1 (KREMEN1 Products)
- Synonyms
- KREMEN1 Protein, krm1 Protein, kremen Protein, kremem1 Protein, KREMEN Protein, KRM1 Protein, AV002070 Protein, Kremen Protein, Krm1 Protein, si:ct737139.1 Protein, si:dkeyp-7c9.1 Protein, kringle containing transmembrane protein 1 Protein, kringle containing transmembrane protein 1 S homeolog Protein, KREMEN1 Protein, kremen1 Protein, Kremen1 Protein, kremen1.S Protein
- Background
- Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).
- Molecular Weight
- 67.4 kDa
- Pathways
- WNT Signaling
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