Quick Overview for LDLR Protein (Myc-DYKDDDDK Tag) (ABIN2724578)
Target
See all LDLR ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This LDLR protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human LDLR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)
LDLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Low Density Lipoprotein Receptor (LDLR) (AA 105-205) protein (GST tag)LDLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (Biotin,His-Avi Tag)LDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His-Avi Tag)LDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR Origin: Cynomolgus Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 1-860) protein (GST tag)LDLR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (Active) protein (His tag)LDLR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His tag)LDLR Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Low Density Lipoprotein Receptor (LDLR) (AA 455-607) protein (His-IF2DI Tag)LDLR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LDLR (Low Density Lipoprotein Receptor (LDLR))
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Alternative Name
- Ldlr
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Background
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
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Molecular Weight
- 93 kDa
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NCBI Accession
- NP_000518
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Pathways
- Hepatitis C, Lipid Metabolism
Target
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