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Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag)

LPIN1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724880
  • Target See all Lipin 1 (LPIN1) Proteins
    Lipin 1 (LPIN1)
    Protein Type
    Recombinant
    Origin
    • 3
    • 3
    • 2
    Human
    Source
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Lipin 1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human LPIN1 / Lipin-1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product LPIN1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Lipin 1 (LPIN1)
    Alternative Name
    Lpin1,lipin-1 (LPIN1 Products)
    Synonyms
    LPIN1 Protein, pap1 Protein, PAP1 Protein, 4631420P06 Protein, Kiaa0188 Protein, Lipin1 Protein, fld Protein, mKIAA0188 Protein, zgc:194552 Protein, zgc:194558 Protein, lipin1 Protein, lipin 1 Protein, phosphatidate phosphatase LPIN1 Protein, LPIN1 Protein, lpin1 Protein, LOC100539289 Protein, Lpin1 Protein
    Background
    This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
    Molecular Weight
    98.5 kDa
    NCBI Accession
    NP_663731
    Pathways
    Monocarboxylic Acid Catabolic Process
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