LRRC8A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for LRRC8A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2724946)
Target
See all LRRC8A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This LRRC8A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human LRRC8A (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
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Alternative Name
- Lrrc8a
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Background
- This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
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Molecular Weight
- 94 kDa
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NCBI Accession
- NP_062540
Target
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