LZTS1 Protein (His tag)

Catalog No. ABIN2725087

This Recombinant LZTS1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for LZTS1 Protein (His tag) (ABIN2725087)

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This LZTS1 protein is labelled with His tag.

Characteristics:

• Recombinant human LZTS1 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: Lzts1

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Molecular Weight: 66.4 kDa

NCBI Accession: NP_066300

Pathways: Synaptic Membrane