MAL Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725234

This Recombinant MAL protein is expressed in HEK-293 Cells.

Quick Overview for MAL Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2725234)

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant A

Purification tag / Conjugate: This MAL protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human MAL (transcript variant a) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MAL (Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL))

Alternative Name: Mal

Background: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Molecular Weight: 16.5 kDa

NCBI Accession: NP_002362

Pathways: Asymmetric Protein Localization