MAX Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
Quick Overview for MAX Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag) (ABIN2725569)
Target
See all MAX ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 4
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Purification tag / Conjugate
- This MAX protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MAX (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MAX (MYC Associated Factor X (MAX))
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Alternative Name
- Max
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Background
- The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 11.3 kDa
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NCBI Accession
- NP_660089
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Pathways
- Mitotic G1-G1/S Phases
Target
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