MFN2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for MFN2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2726077)
Target
See all MFN2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This MFN2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Mitofusin-2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MFN2 (Mitofusin 2 (MFN2))
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Alternative Name
- Mitofusin-2
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Background
- This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
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Molecular Weight
- 86.2 kDa
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NCBI Accession
- NP_055689
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Pathways
- Skeletal Muscle Fiber Development
Target
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