MMP14 Protein (Myc-DYKDDDDK Tag)
Quick Overview for MMP14 Protein (Myc-DYKDDDDK Tag) (ABIN2726152)
Target
See all MMP14 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MMP14 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MMP-14 / MT1-MMP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
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Alternative Name
- Mmp-14,mt1-Mmp
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Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
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Molecular Weight
- 53.8 kDa
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NCBI Accession
- NP_004986
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Pathways
- Autophagy
Target
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