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MMP14 Protein (AA 112-582) (His-SUMO Tag)

MMP14 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709943
  • Target See all MMP14 Proteins
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 112-582
    Origin
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MMP14 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    YAIQGLKWQH NEITFCIQNY TPKVGEYATY EAIRKAFRVW ESATPLRFRE VPYAYIREGH EKQADIMIFF AEGFHGDSTP FDGEGGFLAH AYFPGPNIGG DTHFDSAEPW TVRNEDLNGN DIFLVAVHEL GHALGLEHSS DPSAIMAPFY QWMDTENFVL PDDDRRGIQQ LYGGESGFPT KMPPQPRTTS RPSVPDKPKN PTYGPNICDG NFDTVAMLRG EMFVFKERWF WRVRNNQVMD GYPMPIGQFW RGLPASINTA YERKDGKFVF FKGDKHWVFD EASLEPGYPK HIKELGRGLP TDKIDAALFW MPNGKTYFFR GNKYYRFNEE LRAVDSEYPK NIKVWEGIPE SPRGSFMGSD EVFTYFYKGN KYWKFNNQKL KVEPGYPKSA LRDWMGCPSG GRPDEGTEEE TEVIIIEVDE EGGGAVSAAA VVLPVLLLLL VLAVGLAVFF FRRHGTPRRL LYCQRSLLDK V
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product MMP14 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    Alternative Name
    MMP14 (MMP14 Products)
    Synonyms
    MMP1 Protein, MMP-14 Protein, MMP-X1 Protein, MT-MMP Protein, MT-MMP 1 Protein, MT1-MMP Protein, MT1MMP Protein, MTMMP1 Protein, mmp-x1 Protein, mt1-mmp Protein, mtmmp1 Protein, AI325305 Protein, MT-MMP-1 Protein, sabe Protein, Mt1-mmp Protein, MT-MMPbeta Protein, cb386 Protein, sb:cb386 Protein, wu:fb72b09 Protein, mmp14 Protein, matrix metallopeptidase 14 Protein, matrix metallopeptidase 14 (membrane-inserted) Protein, matrix metallopeptidase 14b (membrane-inserted) Protein, matrix metallopeptidase 14a (membrane-inserted) Protein, matrix metallopeptidase 14 L homeolog Protein, MMP14 Protein, mmp14 Protein, Mmp14 Protein, mmp14b Protein, mmp14a Protein, mmp14.L Protein
    Background
    Ses to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.
    Molecular Weight
    69.8 kDa
    UniProt
    P50281
    Pathways
    Autophagy
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