MSH5 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726437

This Recombinant MSH5 protein is expressed in HEK-293 Cells.

Quick Overview for MSH5 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag) (ABIN2726437)

Target: MSH5 (MutS Homolog 5 (MSH5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 4

Purification tag / Conjugate: This MSH5 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human MSH5 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MSH5 (MutS Homolog 5 (MSH5))

Alternative Name: Msh5

Background: This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.

Molecular Weight: 92.7 kDa

NCBI Accession: NP_751898

Pathways: M Phase