NK2 Homeobox 5 Protein (NKX2-5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2727353

Recombinant NK2 Homeobox 5 protein expressed in HEK-293 Cells.

Quick Overview for NK2 Homeobox 5 Protein (NKX2-5) (Myc-DYKDDDDK Tag) (ABIN2727353)

Target: NK2 Homeobox 5 (NKX2-5)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This NK2 Homeobox 5 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human NKX2-5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NK2 Homeobox 5 (NKX2-5)

Alternative Name: Nkx2-5

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Molecular Weight: 34.7 kDa

NCBI Accession: NP_004378

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development