NOS1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2727468

This Recombinant NOS1 protein is produced in HEK-293 Cells.

Quick Overview for NOS1 Protein (Myc-DYKDDDDK Tag) (ABIN2727468)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This NOS1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human NOS1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Alternative Name: Nos1

Background: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011].

Molecular Weight: 160.8 kDa

NCBI Accession: NP_000611

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction