TR4 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TR4 Protein (Myc-DYKDDDDK Tag) (ABIN2727574)
Target
See all TR4 (NR2C2) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TR4 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human NR2C2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-596) protein (His tag)
custom-made NR2C2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-596) protein (His tag)custom-made NR2C2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-530) protein (GST tag)NR2C2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 3-592), (partial) protein (His tag)NR2C2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
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Alternative Name
- Nr2c2
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Background
- This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 67.2 kDa
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NCBI Accession
- NP_003289
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Pathways
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
Target
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