ORC6 Protein (Myc-DYKDDDDK Tag)
Quick Overview for ORC6 Protein (Myc-DYKDDDDK Tag) (ABIN2727931)
Target
See all ORC6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This ORC6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ORC6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
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Alternative Name
- Orc6
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Background
- The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
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Molecular Weight
- 27.9 kDa
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NCBI Accession
- NP_055136
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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