ORC6 Protein (AA 1-252) (His tag)
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- Target See all ORC6 Proteins
- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-252
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ORC6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMGSELIG RLAPRLGLAE PDMLRKAEEY LRLSRVKCVG LSARTTETSS AVMCLDLAAS WMKCPLDRAY LIKLSGLNKE TYQSCLKSFE CLLGLNSNIG IRDLAVQFSC IEAVNMASKI LKSYESSLPQ TQQVDLDLSR PLFTSAALLS ACKILKLKVD KNKMVATSGV KKAIFDRLCK QLEKIGQQVD REPGDVATPP RKRKKIVVEA PAKEMEKVEE MPHKPQKDED LTQDYEEWKR KILENAASAQ KATAE
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ORC6 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 40 % glycerol, 2 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))
- Alternative Name
- ORC6 (ORC6 Products)
- Synonyms
- Orc6l Protein, CG1584 Protein, DmORC 6 Protein, DmORC6 Protein, Dmel\\CG1584 Protein, ORC Protein, ORC6 Protein, orc6 Protein, rDmORC Protein, ORC6L Protein, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 Protein, ATORC6 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 Protein, T2P11.3 Protein, T2P11_3 Protein, origin recognition complex protein 6 Protein, DDBDRAFT_0186183 Protein, DDBDRAFT_0233113 Protein, DDB_0186183 Protein, DDB_0233113 Protein, LOC100284755 Protein, orc6l Protein, 6720420I10Rik Protein, origin recognition complex, subunit 6 Protein, Origin recognition complex subunit 6 Protein, origin recognition complex subunit 6 Protein, origin recognition complex protein 6 Protein, origin recognition complex subunit Orc6 Protein, Orc6 Protein, ORC6 Protein, CpipJ_CPIJ005016 Protein, SJAG_01267 Protein, orcF Protein, LOC100284755 Protein, orc6 Protein
- Background
- Origin recognition complex subunit 6, also known as ORC6, belongs to the origin recognition complex (ORC). ORC is a highly conserved heterohexameric protein complex that associates with DNA at or near sites of initiation of DNA replication. All six ORC subunits are essential for initiation of DNA replication, and ORC may be involved in regulation of gene expression in response to stress. ORC6 is also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. Recombinant human ORC6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 30.5 kDa (275aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_055136
- UniProt
- Q9Y5N6
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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