OTUD5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for OTUD5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728059)
Target
See all OTUD5 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This OTUD5 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human OTUD5 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- OTUD5 (OTU Domain Containing 5 (OTUD5))
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Alternative Name
- Otud5
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Background
- This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
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Molecular Weight
- 60.4 kDa
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NCBI Accession
- NP_060072
Target
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